Vitamin E inhibition of platelet aggregation is independent of antioxidant activity.

@article{Freedman2001VitaminEI,
  title={Vitamin E inhibition of platelet aggregation is independent of antioxidant activity.},
  author={J. Freedman and J. Keaney},
  journal={The Journal of nutrition},
  year={2001},
  volume={131 2},
  pages={
          374S-7S
        }
}
Vitamin E is the principal lipid-soluble antioxidant in human plasma, and some studies indicate that it may provide cardiovascular protection. To investigate putative mechanisms for vitamin E in this regard, the effect of vitamin E on vascular function and platelet aggregation was examined. In animal models of endothelial dysfunction, vitamin E improved the activity of endothelium-derived nitric oxide, and this effect was not dependent upon the antioxidant protection of LDL. In fact, vitamin E… Expand
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...
1
2
3
4
5
...

References

SHOWING 1-10 OF 11 REFERENCES
Antioxidants and atherosclerotic heart disease.
Dietary and pharmacological antioxidants in atherosclerosis.
  • R. Stocker
  • Medicine, Biology
  • Current opinion in lipidology
  • 1999
...
1
2
...