Vitamin E can improve behavioral tests impairment, cell loss, and dendrite changes in rats' medial prefrontal cortex induced by acceptable daily dose of aspartame.

@article{Rafati2018VitaminEC,
  title={Vitamin E can improve behavioral tests impairment, cell loss, and dendrite changes in rats' medial prefrontal cortex induced by acceptable daily dose of aspartame.},
  author={Ali Rafati and Ali Noorafshan and Mahboubeh Jahangir and Leila Hosseini and Saied Karbalay-Doust},
  journal={Acta histochemica},
  year={2018},
  volume={120 1},
  pages={
          46-55
        }
}
  • Ali Rafati, Ali Noorafshan, +2 authors Saied Karbalay-Doust
  • Published 2018
  • Medicine, Biology
  • Acta histochemica
  • Aspartame is an artificial sweetener used in about 6000 sugar-free products. Aspartame consumption could be associated with various neurological disorders. This study aimed to evaluate the effect of aspartame onmedial Prefrontal Cortex (mPFC) as well as neuroprotective effects of vitamin E. The rats were divided into seven groups, including distilled water, corn oil, vitamin E (100mg/kg/day), and low (acceptable daily dose) and high doses of aspartame (40 and 200mg/kg/day) respectively, with or… CONTINUE READING

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