Vitamin D3 treatment of Crohn's disease patients increases stimulated T cell IL-6 production and proliferation.

Abstract

BACKGROUND Vitamin D3 has shown immune-modulating effects in CD4+ T cells from Crohn's disease patients in vitro. AIM To investigate the effects of in vivo vitamin D3 treatment on T cells in Crohn's disease patients. METHODS Peripheral blood mononuclear cells (PBMC) were isolated at week 0 and at week 26 from 10 vitamin D3- and 10 placebo-treated Crohn… (More)
DOI: 10.1111/j.1365-2036.2010.04463.x

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