Vitamin D3 metabolism in dogs.

  title={Vitamin D3 metabolism in dogs.},
  author={Herman A. W. Hazewinkel and Meropi A Tryfonidou},
  journal={Molecular and cellular endocrinology},
  volume={197 1-2},
Plasma concentrations of the main vitamin D(3) metabolites (i.e., 25(OH)D(3), 1,25(OH)(2)D(3), and 24,25(OH)(2)D(3)) were measured in 14 weeks old large- and small-breed dogs (adult body weight 60 kg vs. 6 kg), raised under the same conditions. Levels of 25(OH)D(3) (approx. 22 microg/l) and 1,25(OH)(2)D(3) (approx. 40 ng/l) were similar in both groups, whereas plasma 24,25(OH)(2)D(3) concentrations were lower in large-breed dogs (7 microg/l vs. 70 microg/l, large- vs. small-breed dogs… CONTINUE READING