Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer

@inproceedings{Refaat2015VitaminDE,
  title={Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer},
  author={Bassem Refaat and Adel Galal Ahmed El-Shemi and Osama Adnan Kensara and Amr Mohamed Aly Mohamed and Shakir Idris and Jawwad Ahmad and Athar Khojah},
  booktitle={Journal of experimental & clinical cancer research : CR},
  year={2015}
}
BACKGROUND Vitamin D3 and its analogues have recently been shown to enhance the anti-tumour effects of 5- Fluorouracil (5-FU) both in vitro and in xenograft mouse model of colon cancer. This study measured the potential mechanism(s) by which vitamin D3 could synergise the tumouricidal activities of 5-FU in azoxymethane (AOM) rat model of colon cancer… CONTINUE READING