Vitamin D3 contributes to enhanced osteogenic differentiation of MSCs under oxidative stress condition via activating the endogenous antioxidant system

@article{Zhou2018VitaminDC,
  title={Vitamin D3 contributes to enhanced osteogenic differentiation of MSCs under oxidative stress condition via activating the endogenous antioxidant system},
  author={Jijun Zhou and Fenghong Wang and Yuanyuan Ma and Furong Wei},
  journal={Osteoporosis International},
  year={2018},
  volume={29},
  pages={1917-1926}
}
SummaryThe anti-oxidative effects of vitamin D3 (Vd3) on mesenchymal stem cells (MSCs) have not been studied before. The present study suggested that Vd3 could not only promote the osteogenic differentiation of MSCs under normal condition but also partly protect it from oxidative stress damage by activating the endogenous antioxidant system.IntroductionEvolving evidence proved that oxidative stress caused by reactive oxygen species (ROS) overproduction might lead to bone loss. Vd3, a commonly… CONTINUE READING
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