Vitamin D3 confers protection from autoimmune encephalomyelitis only in female mice.

@article{Spach2005VitaminDC,
  title={Vitamin D3 confers protection from autoimmune encephalomyelitis only in female mice.},
  author={Karen M. Spach and Colleen Hayes},
  journal={Journal of immunology},
  year={2005},
  volume={175 6},
  pages={4119-26}
}
The prevalence of multiple sclerosis (MS) increases significantly with decreasing UV B light exposure, possibly reflecting a protective effect of vitamin D(3). Consistent with this theory, previous research has shown a strong protective effect 1,25-dihydroxyvitamin D(3) in experimental autoimmune encephalomyelitis (EAE), an MS model. However, it is not known whether the hormone precursor, vitamin D(3), has protective effects in EAE. To address this question, B10.PL mice were fed a diet with or… CONTINUE READING
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