Vitamin D2 analog 19-nor-1,25-dihydroxyvitamin D2: antitumor activity against leukemia, myeloma, and colon cancer cells.

@article{Kumagai2003VitaminDA,
  title={Vitamin D2 analog 19-nor-1,25-dihydroxyvitamin D2: antitumor activity against leukemia, myeloma, and colon cancer cells.},
  author={Takashi Kumagai and J O'kelly and Jonathan Said and H Phillip Koeffler},
  journal={Journal of the National Cancer Institute},
  year={2003},
  volume={95 12},
  pages={896-905}
}
BACKGROUND 1,25-Dihydroxyvitamin D(3) inhibits growth of several types of human cancer cells in vitro, but its therapeutic use is hampered because it causes hypercalcemia. 19-nor-1,25-Dihydroxyvitamin D(2) (paricalcitol) is a noncalcemic vitamin D analog that is approved by the Food and Drug Administration for the treatment of secondary hyperparathyroidism… CONTINUE READING