Vitamin D supplementation for prevention of mortality in adults.

@article{Bjelakovic2014VitaminDS,
  title={Vitamin D supplementation for prevention of mortality in adults.},
  author={Goran Bjelakovic and Lise Lotte Gluud and Dimitrinka Nikolova and Kate Whitfield and J{\o}rn Wetterslev and Rosa Giovanna Simonetti and Marija Dakovi{\'c} Bjelakovi{\'c} and Christian Gluud},
  journal={The Cochrane database of systematic reviews},
  year={2014},
  volume={1},
  pages={
          CD007470
        }
}
BACKGROUND Available evidence on the effects of vitamin D on mortality has been inconclusive. In a recent systematic review, we found evidence that vitamin D3 may decrease mortality in mostly elderly women. The present systematic review updates and reassesses the benefits and harms of vitamin D supplementation used in primary and secondary prophylaxis of mortality. OBJECTIVES To assess the beneficial and harmful effects of vitamin D supplementation for prevention of mortality in healthy… 
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BACKGROUND Ecological and observational studies suggest that low vitamin D status could be associated with higher mortality from life-threatening conditions including cancer, cardiovascular disease,
Vitamin D supplementation for prevention of cancer in adults.
TLDR
TSA of the 18 vitamin D trials shows that the futility area is reached after the 10th trial, allowing us to conclude that a possible intervention effect, if any, is lower than a 5% relative risk reduction.
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