Vitamin D supplementation and body weight status: a systematic review and meta‐analysis of randomized controlled trials

@article{Pathak2014VitaminDS,
  title={Vitamin D supplementation and body weight status: a systematic review and meta‐analysis of randomized controlled trials},
  author={Kaveri Pathak and MJ Soares and E K Calton and Y. Zhao and Jonathan Hallett},
  journal={Obesity Reviews},
  year={2014},
  volume={15}
}
Vitamin D is anticipated to have many extra‐skeletal health benefits. We questioned whether supplementation with the vitamin influenced body weight and composition. A systematic review and meta‐analysis was conducted on high‐quality, randomized controlled trials (RCTs) that had supplemented vitamin D without imposing any caloric restriction. Eighteen trials reporting either body weight, body mass index (BMI), fat mass (FM), percentage fat mass (%FM) or lean body mass (LBM) met our criteria… Expand
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Reductions in body weight and percent fat mass increase the vitamin D status of obese subjects: a systematic review and metaregression analysis.
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A systematic review of the literature over the last 21 years confirmed a volumetric dilution of vitamin D in obesity based on the hypothesis that weight loss, particularly fat loss, would increase serum 25-hydroxyvitamin D (25OHD) in the obese. Expand
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Daily vitamin D3 supplementation vs placebo in the general older population did not improve weight or body composition, and whether supplementalitamin D3 may benefit individuals with normal BMI warrants further study. Expand
Vitamin D status and weight loss: a systematic review and meta-analysis of randomized and nonrandomized controlled weight-loss trials.
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The results indicate that vitamin D status may be marginally improved with weight loss in comparison with weight maintenance under similar conditions of supplemental vitamin D intake, and support the view that the association between obesity and lower serum 25-hydroxyvitamin D may be due to reversed causation with increased adiposity leading to suboptimal concentrations of circulating vitamin D. Expand
Vitamin D supplementation and body fat mass: a systematic review and meta-analysis
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25(OH)D level is inversely correlated with PFM but cholecalciferol supplementation had no effect on PFM, and subgroup and meta-regression analyses indicated that age, latitude, and longitude are not sources of heterogeneity. Expand
Vitamin D status and weight loss : a systematic review and meta-analysis of randomized and nonrandomized controlled weight-loss trials 1 , 2
Background: Obesity is associated with lower concentrations of serum 25-hydroxyvitamin D; however, uncertainty exists as to the direction of causation. To date, meta-analyses of randomized controlled… Expand
Obesity and overweight decreases the effect of vitamin D supplementation in adults: systematic review and meta-analysis of randomized controlled trials
TLDR
The study observed that obesity in adults reduced the effect of vitamin D supplementation, and research should be developed on the optimal dose of vitaminD supplementation for people with obesity. Expand
Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data
TLDR
The fact that most MAs on results from RCTs did not show a beneficial effect does not disprove the hypothesis suggested by observational findings on adverse health outcomes of low 25OHD levels. Expand
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It was shown that whilst a diet containing vitamin D fortified foods does not reduce body weight or BMI, it has beneficial effect on WHR and WC. Expand
The impact of cholecalciferol supplementation on the systemic inflammatory profile: a systematic review and meta-analysis of high-quality randomized controlled trials
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Available high-quality RCTs did not support a beneficial effect of cholecalciferol on systemic IL-6 and CRP and future studies should consider the confounding effects of age, gender and study duration, while possibly targeting an achieved 25(OH)D ⩾80 nmol/l. Expand
Body Mass Index, Vitamin D, and Type 2 Diabetes: A Systematic Review and Meta-Analysis
TLDR
The deficiency of vitamin D is associated with an increased level of BMI in the studies of both diabetic and non-diabetic subjects and reliable evidence from well-designed future randomized controlled trials is required to confirm the findings from observational studies and to find out the potential regulatory effects ofitamin D supplementation to lower BMI. Expand
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