Vitamin D supplementation and body weight status: a systematic review and meta‐analysis of randomized controlled trials

@article{Pathak2014VitaminDS,
  title={Vitamin D supplementation and body weight status: a systematic review and meta‐analysis of randomized controlled trials},
  author={Kaveri Pathak and MJ Soares and E K Calton and Y. Zhao and Jonathan Hallett},
  journal={Obesity Reviews},
  year={2014},
  volume={15}
}
Vitamin D is anticipated to have many extra‐skeletal health benefits. We questioned whether supplementation with the vitamin influenced body weight and composition. A systematic review and meta‐analysis was conducted on high‐quality, randomized controlled trials (RCTs) that had supplemented vitamin D without imposing any caloric restriction. Eighteen trials reporting either body weight, body mass index (BMI), fat mass (FM), percentage fat mass (%FM) or lean body mass (LBM) met our criteria… 
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88 Citations
Highly Influential Citations
2
Background Citations
28
Methods Citations
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Results Citations
4

88 Citations

Reductions in body weight and percent fat mass increase the vitamin D status of obese subjects: a systematic review and metaregression analysis.
Vitamin D status and weight loss: a systematic review and meta-analysis of randomized and nonrandomized controlled weight-loss trials.
TLDR
The results indicate that vitamin D status may be marginally improved with weight loss in comparison with weight maintenance under similar conditions of supplemental vitamin D intake, and support the view that the association between obesity and lower serum 25-hydroxyvitamin D may be due to reversed causation with increased adiposity leading to suboptimal concentrations of circulating vitamin D.
Vitamin D supplementation and body fat mass: a systematic review and meta-analysis
TLDR
25(OH)D level is inversely correlated with PFM but cholecalciferol supplementation had no effect on PFM, and subgroup and meta-regression analyses indicated that age, latitude, and longitude are not sources of heterogeneity.
Vitamin D status and weight loss : a systematic review and meta-analysis of randomized and nonrandomized controlled weight-loss trials 1 , 2
TLDR
The results indicate that vitamin D status may be marginally improved with weight loss in comparison with weight maintenance under similar conditions of supplemental vitamin D intake and support the view that the association between obesity and lower serum 25-hydroxyvitamin D may be due to reversed causation with increased adiposity leading to suboptimal concentrations of circulating vitamin D.
Obesity and overweight decreases the effect of vitamin D supplementation in adults: systematic review and meta-analysis of randomized controlled trials
TLDR
The study observed that obesity in adults reduced the effect of vitamin D supplementation, and research should be developed on the optimal dose of vitaminD supplementation for people with obesity.
Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data
TLDR
The fact that most MAs on results from RCTs did not show a beneficial effect does not disprove the hypothesis suggested by observational findings on adverse health outcomes of low 25OHD levels.
The effect of vitamin D fortified products on anthropometric indices: A systematic review and meta-analysis.
The Effect of Vitamin D Supplementation on the Glycemic Status and the Percentage of Body Fat Mass in Adults with Prediabetes: A Randomized Clinical Trial
TLDR
It is demonstrated that 1000 IU vitamin D supplementation for 3 months can decrease the insulin resistance in individuals with prediabetes; however, it has no significant eect on body fat mass percentage.
Impact of vitamin D supplementation on adiposity in African-Americans
TLDR
In overweight African-Americans, short-term high-dose vitamin D supplementation did not alter BMI and did not cause any significant changes in BMI.
The effect of vitamin D supplementation on selected inflammatory biomarkers in obese and overweight subjects: a systematic review with meta-analysis
TLDR
This meta-analysis suggests that supplementation with vitamin D does not have a significant influence on changes in the concentration of selected inflammatory biomarkers in the obese and overweight subjects.
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