Vitamin D status is associated with muscle strength and quality of life in patients with COPD: a seasonal prospective observation study
@article{Carson2018VitaminDS, title={Vitamin D status is associated with muscle strength and quality of life in patients with COPD: a seasonal prospective observation study}, author={E. L. Carson and L. Kirsty Pourshahidi and Sharon M. Madigan and Francina R. Baldrick and Martin Kelly and Eamon Laird and Martin Healy and J J Strain and Maria S. Mulhern}, journal={International Journal of Chronic Obstructive Pulmonary Disease}, year={2018}, volume={13}, pages={2613 - 2622} }
Background Owing to hospitalization, reduced functional capacity and consequently, less sunlight exposure, suboptimal vitamin D status (25-hydroxyvitamin D [25(OH)D]⩽50 nmol/L) is prevalent among COPD patients. Objective This study aimed to investigate seasonal changes in vitamin D status and any associated changes in fat-free mass (FFM), muscle strength and quality of life (QoL) in COPD patients. Patients and methods COPD patients living in Northern Ireland (n=51) completed study visits at the…
14 Citations
Comparison of the association between circulating vitamin D3 levels and clinical outcomes in patients with asthma and chronic obstructive pulmonary disease: a prospective observational study.
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Lower concentrations of plasma 25(OH)D3 contributed to lower HR-QOL in patients with asthma, and were associated with severity and risk of future exacerbations in Patients with COPD.
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Vitamin D deficiency was associated with increased respiratory symptoms, decreased functional status, increased frequency of severe exacerbations, as well as airway wall thickening on chest CT scans and the potential impact of vitamin D supplementation to improve disease outcomes.
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Higher 25-OH-vitamin D levels are associated with more favorable respiratory-specific symptoms and quality-of-life assessments in middle-age but not older COPD individuals, when controlled for clinically relevant covariates.
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Low vitamin D levels are associated with changes in lung function in cases of COPD as well as healthy controls and routine assessment of vitamin D may be undertaken to obviate the effects of low vitmain D level on lung function.
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This study investigates the efficacy of 1 year targeted nutrient supplementation on physical activity level and health-related quality of life in patients with COPD and results will be disseminated through presentations at (inter)national conferences and through peer-reviewed journals.
Bone mineral density and vitamin D levels in patients with group a COPD
- Medicine, BiologyThe aging male : the official journal of the International Society for the Study of the Aging Male
- 2019
Vitamin D deficiency/insufficiency is prevalent in COPD patients, and BMD decreases in the early period of the disease, according to a case-control study involving 33 males diagnosed with Group A COPD and 44 age-matched healthy males.
High parathyroid hormone predicts exacerbations in COPD patients with hypovitaminosis D.
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Correlation of severity of chronic obstructive pulmonary disease with serum vitamin-D level
- MedicineJournal of family medicine and primary care
- 2019
The serum vitamin D level and its correlation with severity of COPd as assessed by spirometry, COPD assessment test (CAT) and exercise capacity and BMI of COPD patients was studied.
Nutritional support in chronic obstructive pulmonary disease (COPD): an evidence update.
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It is likely that targeted multi-modal interventions are required to address energy and protein imbalance, specific nutrient deficiencies, reduced androgens and targeted exercise training to effectively managing the common and costly problem of nutritional depletion in COPD.
A Comprehensive Review on Vitamin D as a Novel Therapeutic Agent in Chronic Obstructive Pulmonary Disease
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The hypothesis that vitamin D can act as an effective therapeutic agent for COPD is tested by reviewing the correlation between the two and effectiveness along with the safety of supplemental vitamin D when used to treat chronic bronchitis and emphysema through clinical trials.
References
SHOWING 1-10 OF 67 REFERENCES
Supplemental vitamin D and physical performance in COPD: a pilot randomized trial
- MedicineInternational journal of chronic obstructive pulmonary disease
- 2013
Among patients with severe COPD, 2000 IU of daily vitamin D for 6 weeks increased 25(OH)D to a level widely considered as normal, however, compared with placebo, short-term vitamin D supplementation had no discernible effect on a simple measure of physical performance.
Vitamin D status is associated with bone mineral density and functional exercise capacity in patients with chronic obstructive pulmonary disease
- MedicineAnnals of medicine
- 2013
The majority of COPD patients had vitamin D deficiency, and plasma 25(OH)D concentration was positively associated with bone density and exercise capacity, and intervention studies are necessary to determine whether vitamin D supplementation is of benefit in the prevention or treatment of osteoporosis and poor exercise capacity in patients with COPD.
Effects of daily vitamin D supplementation on respiratory muscle strength and physical performance in vitamin D-deficient COPD patients: a pilot trial
- MedicineInternational journal of chronic obstructive pulmonary disease
- 2017
Vitamin D supplementation did not affect (respiratory) muscle strength or physical performance in this pilot trial in vitamin D-deficient COPD patients, and primary outcomes did not differ between the groups after 6 months.
Vitamin D and skeletal muscle strength and endurance in COPD
- Medicine, BiologyEuropean Respiratory Journal
- 2012
In contrast with healthy controls, muscle strength is not associated with vitamin D levels in COPD, which may represent vitamin D resistance.
Vitamin D status and physical function in older Finnish people: A one-year follow-up study.
- MedicineArchives of gerontology and geriatrics
- 2015
Low vitamin D status is associated with reduced muscle mass and impaired physical performance in frail elderly people
- MedicineEuropean Journal of Clinical Nutrition
- 2013
In this frail elderly population, 25(OH)D status is low and suggests a modest association with reduced ALM and impaired physical performance, which highlights the need for well-designed intervention trials to assess the impact of vitamin D supplementation in pre-frail and frail elderly people.
Hypovitaminosis D is associated with a reduction in upper and lower limb muscle strength and physical performance in post-menopausal women: a retrospective study
- Medicine, BiologyAging Clinical and Experimental Research
- 2015
The data showed that post-menopausal women with hypovitaminosis D had worse upper and lower limb muscle strength and physical performance than subjects with normal levels of 25(OH)D3.
Chronic Obstructive Pulmonary Disease Is Associated with Low Levels of Vitamin D
- MedicinePloS one
- 2012
COPD was associated with an increased risk of vitamin D deficiency, and important disease characteristics were significantly related to 25(OH)D levels.
Adiposity in relation to vitamin D status and parathyroid hormone levels: a population-based study in older men and women.
- MedicineThe Journal of clinical endocrinology and metabolism
- 2005
OBJECTIVE
In small case-control studies, obesity was associated with worse vitamin D status. Our aim was to assess the association of adiposity (anthropometric measures as well as dual energy x-ray…
Relationship between vitamin D and lung function, physical performance and balance on patients with stage I-III chronic obstructive pulmonary disease.
- MedicineRevista da Associacao Medica Brasileira
- 2015
Patients with COPD had worst physical functioning, poor balance and less muscle strength, and severe disturbed lung and peripheral muscle functions are more pronounced in COPD patients with vitamin D deficiency.