Vitamin D signaling pathway plays an important role in the development of heart failure after myocardial infarction.

@article{Bae2013VitaminDS,
  title={Vitamin D signaling pathway plays an important role in the development of heart failure after myocardial infarction.},
  author={Soochan Bae and Sylvia S. Singh and Hyeon Yu and Ji Yoo Lee and Byung Ryul Cho and Peter M. Kang},
  journal={Journal of applied physiology},
  year={2013},
  volume={114 8},
  pages={979-87}
}
Accumulating evidence suggests that vitamin D deficiency plays a crucial role in heart failure. However, whether vitamin D signaling itself plays an important role in cardioprotection is poorly understood. In this study, we examined the mechanism of modulating vitamin D signaling on progression to heart failure after myocardial infarction (MI) in mice. Vitamin D signaling was activated by administration of paricalcitol (PC), an activated vitamin D analog. Wild-type (WT) mice underwent sham or… CONTINUE READING
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