Vitamin D receptor polymorphisms and the risk of cutaneous melanoma: a systematic review and meta-analysis.

@article{Mocellin2008VitaminDR,
  title={Vitamin D receptor polymorphisms and the risk of cutaneous melanoma: a systematic review and meta-analysis.},
  author={Simone Mocellin and Donato Nitti},
  journal={Cancer},
  year={2008},
  volume={113 9},
  pages={2398-407}
}
It has been hypothesized that polymorphisms in the vitamin D receptor (VDR) gene affect the risk of developing melanoma. However, results often are conflicting, and no meta-analysis has been performed to date on published data. Six studies (cases, 2152; controls, 2410) that investigated the association between 5 VDR polymorphisms (TaqI, FokI, BsmI, EcoRV, and Cdx2) and the risk of melanoma were retrieved and analyzed. The model-free approach was applied to meta-analyze these molecular… CONTINUE READING

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