Vitamin D receptor initiation codon polymorphism, bone density and inflammatory activity of patients with ankylosing spondylitis

@article{ObermayerPietsch2003VitaminDR,
  title={Vitamin D receptor initiation codon polymorphism, bone density and inflammatory activity of patients with ankylosing spondylitis},
  author={Barbara Obermayer-Pietsch and Uwe Lange and Gerlinde Tauber and Gerwig Fr{\"u}hauf and Astrid Fahrleitner and Harald Dobnig and Josef Hermann and Ferdinand Aglas and Joachim Teichmann and Gunter Neeck and Georg Leb},
  journal={Osteoporosis International},
  year={2003},
  volume={14},
  pages={995-1000}
}
Osteoporosis is a common finding in ankylosing spondylitis (AS) and may contribute to spinal deformity and bone pain. Bone metabolism as well as inflammatory processes are influenced by the vitamin D receptor gene (VDR). We investigated initiation codon (FokI) and 3’UTR (BsmI) polymorphisms of the VDR for whether there could be an association with bone mineral density (BMD) in relation to bone metabolism or inflammatory activity in patients with AS. In this study, 104 patients with AS (m/w 71… CONTINUE READING
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  • Arthritis Rheum
  • 2001
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