Vitamin D receptor gene variability as a factor influencing bone mineral density in pediatric patients

@article{JakubowskaPietkiewicz2012VitaminDR,
  title={Vitamin D receptor gene variability as a factor influencing bone mineral density in pediatric patients},
  author={Elżbieta Jakubowska-Pietkiewicz and Wojciech M Młynarski and Izabela Klich and Wojciech Fendler and Danuta Chlebna-Sok{\'o}ł},
  journal={Molecular Biology Reports},
  year={2012},
  volume={39},
  pages={6243-6250}
}
To determine the relationship between the polymorphism of vitamin D receptor gene and the bone mineral density in children. The study group consisted of 395 children aged 6–18 years. All patients underwent genotyping using the PCR-RFLP method within polymorphic loci BsmI (rs1544410), FokI (rs2228570), ApaI (rs7975232) and Taq I (rs731236) of the VDR gene. The BMD (g/cm2, Z score) and BMC (g, Z score) by DXA method, as well as Z scores of the BUA, SOS and Stiffness ultrasound parameters were… CONTINUE READING
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