Vitamin D receptor gene polymorphisms and Parkinson's disease in a population with high ultraviolet radiation exposure.

@article{Gatto2015VitaminDR,
  title={Vitamin D receptor gene polymorphisms and Parkinson's disease in a population with high ultraviolet radiation exposure.},
  author={N M Gatto and Janet S. Sinsheimer and Myles G. Cockburn and Loraine A. Escobedo and Yvette M. Bordelon and Beate R. Ritz},
  journal={Journal of the neurological sciences},
  year={2015},
  volume={352 1-2},
  pages={88-93}
}
INTRODUCTION A high prevalence of vitamin D deficiency has been reported in Parkinson's disease (PD). Epidemiologic studies examining variability in genes involved in vitamin D metabolism have not taken into account level of exposure to ultraviolet radiation (UVR). We examined whether exposure to UVR (as a surrogate for vitamin D levels) and variations in the vitamin D receptor gene (VDR) are associated with PD. METHODS Within a geographical information system (GIS) we linked participants… CONTINUE READING
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