Vitamin D receptor gene polymorphism(s) and breast cancer risk in north Indians.

@article{Chakraborty2009VitaminDR,
  title={Vitamin D receptor gene polymorphism(s) and breast cancer risk in north Indians.},
  author={Anurupa Chakraborty and Ashwani K Mishra and Abha Soni and Thodum Regina and Ravindra Singh Mohil and Dinesh Bhatnagar and Anil K Bhatnagar and Chintamani Chintamani and Prakash Chandra Sharma and Sunita Saxena},
  journal={Cancer detection and prevention},
  year={2009},
  volume={32 5-6},
  pages={386-94}
}
BACKGROUND Vitamin D (1,25-dihydroxyVitamin D3) has shown experimentally anticarcinogenic effects and is thought to protect against breast cancer. The actions of Vitamin D are mediated via the Vitamin D receptor (VDR), and the polymorphisms at 3'UTR region of this gene are associated with the risk and progression of breast carcinoma. The current study is an attempt to examine the association of these variations with breast cancer risk in north Indians. METHODS A total of 160 cases and 140… CONTINUE READING

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