Vitamin D receptor (VDR) gene polymorphism influences the risk of osteoporosis in postmenopausal women of Northwest India.

@article{Singh2013VitaminDR,
  title={Vitamin D receptor (VDR) gene polymorphism influences the risk of osteoporosis in postmenopausal women of Northwest India.},
  author={Monica Singh and Puneetpal Singh and Surinder Singh and Pawan Kumar Juneja and Taranpal Kaur},
  journal={Archives of osteoporosis},
  year={2013},
  volume={8},
  pages={147}
}
SUMMARY The influence of VDR gene for the risk of osteoporosis has remained inconclusive. VDR gene polymorphism in relation to BMD in postmenopausal women of Northwest India revealed a susceptibility haplotype AGT. Possession of this haplotype exacerbates the risk of osteoporosis by 2.8 times, which manifests in recessive mode of inheritance. PURPOSE The purpose of this study is to understand the influence of coordinated effect of various single nucleotide polymorphisms (SNPs) within vitamin… CONTINUE READING