Vitamin D poisoning by table sugar

@article{Vieth2002VitaminDP,
  title={Vitamin D poisoning by table sugar},
  author={R. Vieth and Tanya R Pinto and B. Reen and M. M. Wong},
  journal={The Lancet},
  year={2002},
  volume={359}
}
In June 1999, a 29-year-old man came to the emergency department with right-sided flank pain, conjunctivitis, anorexia, fever, chills, increased thirst, and vomiting. He had lost 5 kg in weight, and was in acute renal failure. He was treated with steroids and discharged. In October, 1999, his 63-year-old father came to the emergency department with similar complaints. He was also in acute renal failure and denied a history of renal stones. showed the same biochemical profile. Kidney biopsies of… Expand
Acute Vitamin D Intoxication in a Child
TLDR
This case highlights the need for caution when using imported and/or unregulated medicines, as well as the dangers of parental dosing errors, in a previously healthy, 2-year-old boy with resistant hypercalcemia and hypertension resulting from an unintentional overdose with an imported vitamin D supplement. Expand
Unusually prolonged vitamin D intoxication after discontinuation of vitamin D: possible role of primary hyperparathyroidism
TLDR
It seems that an underlying primary hyperparathyroidism that was masked initially by the hypercalcemia of vitamin D intoxication was responsible for the unusually prolonged half-life of 25(OH)D in the blood. Expand
Vitamin D Intoxication Due to an Erroneously Manufactured Dietary Supplement in Seven Children
TLDR
In conclusion, errors in manufacturing of dietary supplements may be a cause of VDI in children and Physicians should be aware of this possibility in unexplained VDI cases and repeatedly question the families about dietary supplement use. Expand
Toxicity of Vitamin D
TLDR
It is reasonable to increase the upper limit for vitamin D to at least 10,000 IU/day, because the production of vitamin D in the skin is controlled by sunlight and there is no concern about making too much ofitamin D from excessive exposure to sunlight. Expand
Vitamins D Toxicity in Paediatric Age Group: A Retrospective Cross Sectional Study
  • Dr Pooja Mishra
  • 2020
Background: Vitamin D is an essential element for body health with its supplements generally administered to prevent vitamin D deficiency. Since these supplements are available in domestic settings,Expand
Hypercalcemia Due to Vitamin D Toxicity
Abstract Although vitamin D toxicity is an uncommon cause of hypercalcemia, it becomes a consideration after exclusion of the more frequent causes such as primary hyperparathyroidism and malignancy.Expand
Age-related changes in the 25-hydroxyvitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D.
TLDR
All age groups exhibit a high prevalence of 25(OH)D insufficiency and secondary hyperparathyroidism, and older adults are just as efficient in maintaining 25( OH)D, but they need more vitamin D to produce the higher vitamin D concentrations required to overcome the hyperparathiroidism associated with their diminishing renal function. Expand
Safety of vitamin D 3 in adults with multiple sclerosis 1 – 3
Background: Vitamin D3 may have therapeutic potential in several diseases, including multiple sclerosis. High doses of vitamin D3 may be required for therapeutic efficacy, and yet tolerability—in theExpand
Vitamin D Toxicity
  • Kenneth Lim, R. Thadhani
  • Medicine
  • Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
  • 2020
TLDR
Clinicians are now faced with the challenge of managing this condition that can present on a spectrum from asymptomatic to acute life-threatening complications. Expand
Hypercalcemia and a “no observed adverse effect level” intake of vitamin D
  • R. Vieth
  • Medicine
  • Canadian Medical Association Journal
  • 2019
TLDR
The patient had been taking 8000–10 000 IU of vitamin D daily for 2.5 years, during which time serum creatinine levels were higher than normal, and the patient was diagnosed with vitamin D toxicity. Expand
...
1
2
3
4
5
...

References

SHOWING 1-5 OF 5 REFERENCES
A family with massive acute vitamin D intoxication
TLDR
Before phosphate therapy it was shown that both parents were in strongly negative calcium balance, indicating that the vitamin D was mobilizing calcium from bone, and neutral phosphate was successful, although necessary for 9 months. Expand
Vitamin D intoxication associated with an over-the-counter supplement.
TLDR
A patient with hypercalcemia associated with the ingestion of an over-the-counter vitamin D supplement is described, which is lifesaving at physiologic levels and dangerous at megavitamin levels. Expand
An outbreak of hypervitaminosis D associated with the overfortification of milk from a home-delivery dairy.
TLDR
The overfortification of milk with vitamin D can lead to hypervitaminosis D, manifested by severe illness and death, and highlights the need for monitoring the fortification process and enforcing the upper limit for vitamin D addition to milk. Expand
Serum Levels of Free 1,25-Dihydroxyvitamin D in Vitamin D Toxicity
TLDR
This hypothesis that the high levels of 25-OHD could cause an increase in free levels of 1,25-(OH)2D (despite normal total levels), which might be responsible for the changes in calcium homeostasis is tested. Expand
Efficacy and safety of vitamin D 3 intake exceeding the lowest observed adverse effect level 1 – 3
Academy of Sciences states that 95 ␮g vitamin D/d is the lowest observed adverse effect level (LOAEL). Objective: Our objective was to assess the efficacy and safety of prolonged vitamin D 3 intakesExpand