Vitamin D insufficiency and musculoskeletal health in children and adolescents

  title={Vitamin D insufficiency and musculoskeletal health in children and adolescents},
  author={Ghada El-Hajj Fuleihan and Reinhold Vieth},
A large body of data demonstrates a high prevalence worldwide of hypovitaminosis D in children and adolescents, at a critical time of bone mass accrual. Increasing evidence supports a deleterious effect of vitamin D insufficiency on musculoskeletal health in this age group based on cross-sectional studies, studies relating vitamin D to biochemical variables in the homeostatic pathway for vitamin D physiology (PTH, calcitriol, bone remodeling). Two recent randomized interventional trials show… CONTINUE READING
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