Vitamin D inhibits myometrial and leiomyoma cell proliferation in vitro.

@article{Bluer2009VitaminDI,
  title={Vitamin D inhibits myometrial and leiomyoma cell proliferation in vitro.},
  author={Merja Bl{\"a}uer and P{\"a}ivi H. Rovio and Timo J Ylikomi and Pentti K. Heinonen},
  journal={Fertility and sterility},
  year={2009},
  volume={91 5},
  pages={1919-25}
}
OBJECTIVE To determine the effect of 1,25(OH)(2)D(3) and 25(OH)D(3) vitamin D derivates on the growth of leiomyoma and myometrial cells in vitro. DESIGN In vitro study. SETTING Cell biology research laboratory. PATIENT(S) Six premenopausal women with uterine leiomyomas undergoing hysterectomy. INTERVENTION(S) Samples of leiomyomas and normal myometrial tissue were obtained, and paired cultures were established. MAIN OUTCOME MEASURE(S) A colorimetric crystal violet assay to determine… CONTINUE READING