Vitamin D in the healthy and inflamed central nervous system: access and function.

@article{Smolders2011VitaminDI,
  title={Vitamin D in the healthy and inflamed central nervous system: access and function.},
  author={Joost Smolders and Stine Marit Moen and Jan Damoiseaux and Inge Huitinga and Trygve Holm\oy},
  journal={Journal of the neurological sciences},
  year={2011},
  volume={311 1-2},
  pages={37-43}
}
High exposure to vitamin D may protect against development and progression of multiple sclerosis (MS), possibly through the immunomodulatory properties of its biologically active metabolite 1,25-dihydroxyvitamin D. So far, most studies on the possible mechanisms for vitamin D involvement in MS have focused on immune modulation outside the central nervous system (CNS). However, vitamin D may also interfere with the pathophysiology of MS within the CNS. In this review, the potential presence and… CONTINUE READING