Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis.

@article{Ooi2010VitaminDD,
  title={Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis.},
  author={Li Laine Ooi and Hong Zhou and Robert Kalak and Yu Zheng and Arthur D. Conigrave and Markus J Seibel and Colin Robert Dunstan},
  journal={Cancer research},
  year={2010},
  volume={70 5},
  pages={
          1835-44
        }
}
Vitamin D exerts antiproliferative, prodifferentiation, and proapoptotic effects on nonclassic target tissues such as breast. Blood levels of 25-hydroxyvitamin D [25(OH)D], the most sensitive indicator of vitamin D status, are inversely correlated with breast cancer risk; however, a causal relationship between vitamin D deficiency and breast cancer growth in bone has not been assessed. We examined the effect of vitamin D deficiency on the intraskeletal growth of the human breast cancer cell… CONTINUE READING

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