Vitamin D deficiency in childhood obesity is associated with high levels of circulating inflammatory mediators, and low insulin sensitivity

@article{Reyman2014VitaminDD,
  title={Vitamin D deficiency in childhood obesity is associated with high levels of circulating inflammatory mediators, and low insulin sensitivity},
  author={Marta Reyman and Annemarie A. Verrijn Stuart and Marieke van Summeren and Maryam Rakhshandehroo and Roos Nuboer and Femke de Boer and Henk-Jan van den Ham and Eric Kalkhoven and Berent Prakken and Henk S Schipper},
  journal={International Journal of Obesity},
  year={2014},
  volume={38},
  pages={46-52}
}
Hypothesis:Childhood obesity is accompanied by low-grade systemic inflammation, which contributes to the development of insulin resistance and cardiovascular complications later in life. As vitamin D exhibits profound immunomodulatory functions and vitamin D deficiency is highly prevalent in childhood obesity, we hypothesized that vitamin D deficiency in childhood obesity coincides with enhanced systemic inflammation and reduced insulin sensitivity.Methods:In a cross-sectional study of 64 obese… CONTINUE READING
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Citations

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SHOWING 1-10 OF 19 CITATIONS

Prevalence of vitamin D deficiency and its association with metabolic derangements among children with obesity

S G S Adikaram, D B D L Samaranayake, +3 authors V Pujitha Wickramasinghe
  • BMC pediatrics
  • 2019
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CITES BACKGROUND

Obesity is associated with vitamin D deficiency in Danish children and adolescents.

Johanne Lind Plesner, Maria Mørch Dahl, +5 authors Jens-Christian Holm
  • Journal of pediatric endocrinology & metabolism : JPEM
  • 2018

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