Vitamin D deficiency and hypocalcemia in an infant with newly diagnosed AML.

Abstract

We report a 4-month-old male presenting with hypocalcemia, hyperleukocytosis, and newly diagnosed acute myeloid leukemia. He received chemical leukoreduction through low-dosed cytarabine, with appropriate decrease in his white blood cell count and development of subsequent symptomatic hypocalcemia, which did not normalize until the underlying vitamin D deficiency was addressed. A single dose of cholecalciferol raised the serum calcium concentration to an appropriate level within 48 hours. For infants with newly diagnosed leukemia and prolonged hypocalcemia, vitamin D deficiency should be considered in the differential diagnosis and managed appropriately.

DOI: 10.1097/MPH.0b013e31828e51cc

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Cite this paper

@article{Cook2014VitaminDD, title={Vitamin D deficiency and hypocalcemia in an infant with newly diagnosed AML.}, author={Cathleen Cook and Valeria Alejandra Bernardo and John Shelso and Raul C. Ribeiro}, journal={Journal of pediatric hematology/oncology}, year={2014}, volume={36 2}, pages={e118-20} }