Vitamin D deficiency and depression in adults: systematic review and meta-analysis

@article{Anglin2013VitaminDD,
  title={Vitamin D deficiency and depression in adults: systematic review and meta-analysis},
  author={Rebecca E. S. Anglin and Zainab Samaan and Stephen D. Walter and Sarah Diana McDonald},
  journal={British Journal of Psychiatry},
  year={2013},
  volume={202},
  pages={100 - 107}
}
Background There is conflicting evidence about the relationship between vitamin D deficiency and depression, and a systematic assessment of the literature has not been available. Aims To determine the relationship, if any, between vitamin D deficiency and depression. Method A systematic review and meta-analysis of observational studies and randomised controlled trials was conducted. Results One case-control study, ten cross-sectional studies and three cohort studies with a total of 31 424… 
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563 Citations
Highly Influential Citations
16
Background Citations
194
Methods Citations
17
Results Citations
33

563 Citations

Vitamin D deficiency and depressive symptoms: meta-analysis of studies .
TLDR
The analysis of available literature seems to indicate that there is an association between risk of depression and vitamin D deficiency, however, current literature does not give the possibility to state explicitly what is the exact mechanism and direction of this dependency.
Association between vitamin D deficiency and antepartum and postpartum depression: a systematic review and meta-analysis of longitudinal studies
TLDR
The low status of maternal vitamin D could be an adverse factor for postpartum depression, but the available evidence suggested no association between vitamin D deficiency and depressive symptoms during pregnancy.
Effect of vitamin D supplementation on the incidence and prognosis of depression: An updated meta-analysis based on randomized controlled trials
TLDR
Whether suffering from depression or not, individuals with low vitamin D levels, dose >2,800 IU, intervention duration ≥8 weeks, and all females are most likely to benefit from vitamin D supplementation.
Vitamin D Supplementation for Depressive Symptoms: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
TLDR
Vitamin D supplementation may be effective for reducing depressive symptoms in patients with clinically significant depression; however, further high-quality research is needed.
Vitamin D Deficiency and Depression: A Short Review Article
TLDR
Although some studies have shown an association between depression and vitamin D deficiency, it still cannot be indisputably concluded that augmenting the levels of vitamin D alone alleviate depression.
Vitamin D Deficiency and Antenatal and Postpartum Depression: A Systematic Review
TLDR
A significant association between vitamin D status and AD and PD is indicated, and results of this systematic review vary, they indicate a significant association.
Association between Depressive Symptoms and Vitamin D Deficiency in Adults with Overweight or Obesity
TLDR
A significant association between low vitamin D levels and depression in adults with overweight or obesity is suggested, and further studies are needed to elucidate the association between vitamin D status and depression according to body weight status.
The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials.
TLDR
Despite high heterogeneity, vitamin D supplementation ≥ 2,000 IU/day appears to reduce depressive symptoms and future research should investigate possible benefits of augmenting standard treatments with vitamin D in clinical depression.
Vitamin D and Depression
TLDR
Considering research results of a potential inverse association between vitamin D level and prevalence of depression, it is important to advance the understanding of the role of vitamin D in depression and conduct well-designed prospective trials in the Asian population.
Vitamin D and depression.
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References

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TLDR
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TLDR
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TLDR
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TLDR
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