Vitamin D and the skin

@article{Bikle2009VitaminDA,
  title={Vitamin D and the skin},
  author={Daniel D. Bikle},
  journal={Journal of Bone and Mineral Metabolism},
  year={2009},
  volume={28},
  pages={117-130}
}
  • D. Bikle
  • Published 27 January 2010
  • Biology, Medicine
  • Journal of Bone and Mineral Metabolism
The keratinocytes of the skin are unique in being not only the primary source of vitamin D for the body, but also possessing the enzymatic machinery to metabolize vitamin D to active metabolites [in particular, 1,25 dihydroxyvitamin D (1,25(OH)2D)] and the vitamin D receptor (VDR) that enables the keratinocytes to respond to the 1,25(OH)2D they produce. Numerous functions of the skin are regulated by vitamin D and/or its receptor: these include inhibition of proliferation, stimulation of… 
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References

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TLDR
A number of exciting discoveries have been made that have enhanced the understanding of mechanisms involved in the pleiotropic actions of 1,25(OH)2D3, including the epithelial calcium channel and in the distal nephron.
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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