Vitamin D and the skin

@article{Bikle2009VitaminDA,
  title={Vitamin D and the skin},
  author={D. Bikle},
  journal={Journal of Bone and Mineral Metabolism},
  year={2009},
  volume={28},
  pages={117-130}
}
  • D. Bikle
  • Published 2009
  • Biology, Medicine
  • Journal of Bone and Mineral Metabolism
The keratinocytes of the skin are unique in being not only the primary source of vitamin D for the body, but also possessing the enzymatic machinery to metabolize vitamin D to active metabolites [in particular, 1,25 dihydroxyvitamin D (1,25(OH)2D)] and the vitamin D receptor (VDR) that enables the keratinocytes to respond to the 1,25(OH)2D they produce. Numerous functions of the skin are regulated by vitamin D and/or its receptor: these include inhibition of proliferation, stimulation of… Expand
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