Vitamin D and its receptor during late development.

  title={Vitamin D and its receptor during late development.},
  author={David Goltzman and Geoffrey N Hendy and John H. White},
  journal={Biochimica et biophysica acta},
  volume={1849 2},
Expression of the vitamin D receptor (VDR) is widespread but may vary depending on the developmental stage of the animal, and therefore may differentially influence phenotypic function. Thus, the major role of the 1,25-dihydroxyvitamin D [1,25(OH)2D]/VDR system is to regulate mineral and skeletal homeostasis, although mainly after birth. Post-natally, under conditions of low dietary calcium, the 1,25(OH)2D/VDR system enhances intestinal transcellular transport of calcium and possibly… CONTINUE READING
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