Vitamin D and immune function: understanding common pathways.

  title={Vitamin D and immune function: understanding common pathways.},
  author={Daniel D Bikle},
  journal={Current osteoporosis reports},
  volume={7 2},
Vitamin D, acting through its active metabolite 1,25(OH)(2)D(3), exerts its influence on many physiologic processes in addition to the regulation of calcium and phosphate homeostasis. These processes include the immune system. Both the adaptive and innate immune systems are affected by 1,25(OH)(2)D(3) and its receptor, and the cells involved express not only the vitamin D receptor but also, in most cases, the enzyme CYP27B1, which produces 1,25(OH)(2)D(3). Both the vitamin D receptor and… CONTINUE READING


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