Vitamin D and calcium-sensing receptor genotypes in men and premenopausal women with low bone mineral density.


BACKGROUND Genetic factors have been shown to play a major role in the development of peak bone mass, with hereditability accounting for about 50-85% of the variance in bone mass. Numerous candidate genes involved in osteoporosis have been proposed, but the precise genes and their relative contribution remain unknown. OBJECTIVES To gain insight into the… (More)


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