Vitamin D and breast cancer: insights from animal models.

  title={Vitamin D and breast cancer: insights from animal models.},
  author={J Luckey Welsh},
  journal={The American journal of clinical nutrition},
  volume={80 6 Suppl},
1alpha,25-dihydroxyvitamin D3 [1,25(OH)2D3[, the biologically active form of vitamin D that interacts with the vitamin D receptor (VDR), is a coordinate regulator of proliferation, differentiation, and survival of breast cancer cells. Therefore, vitamin D compounds that bind and activate VDRs offer promise as therapeutic agents for the treatment of established breast cancer. In addition, epidemiologic, clinical, and animal studies suggested that vitamin D status is important for protection… CONTINUE READING