Vitamin D Deficiency and Risk of Cardiovascular Disease

@article{Wang2008VitaminDD,
  title={Vitamin D Deficiency and Risk of Cardiovascular Disease},
  author={Thomas J. Wang and Michael J. Pencina and Sarah L Booth and Paul F. Jacques and Erik Ingelsson and Katherine J. Lanier and Emelia J. Benjamin and Ralph B. D'Agostino and Myles Wolf and Ramachandran S. Vasan},
  journal={Circulation},
  year={2008},
  volume={117},
  pages={503-511}
}
Background— Vitamin D receptors have a broad tissue distribution that includes vascular smooth muscle, endothelium, and cardiomyocytes. A growing body of evidence suggests that vitamin D deficiency may adversely affect the cardiovascular system, but data from longitudinal studies are lacking. Methods and Results— We studied 1739 Framingham Offspring Study participants (mean age 59 years; 55% women; all white) without prior cardiovascular disease. Vitamin D status was assessed by measuring 25… 

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