Vitamin D Deficiency Increases Lipogenesis and Reduces Beta-Oxidation in the Liver of Diet-Induced Obese Mice.

@article{Borges2018VitaminDD,
  title={Vitamin D Deficiency Increases Lipogenesis and Reduces Beta-Oxidation in the Liver of Diet-Induced Obese Mice.},
  author={Celina Carvalho Borges and Andreza Fernandes Salles and Isabele Bringhenti and Carlos Alberto Mandarim-de-Lacerda and M{\'a}rcia Barbosa {\'A}guila},
  journal={Journal of nutritional science and vitaminology},
  year={2018},
  volume={64 2},
  pages={
          106-115
        }
}
The study was conducted to understand better the mechanisms involved in liver changes when there is a combination of diet-induced obesity (DIO) and vitamin D deficiency (VDD). After 8 wk of feeding a control diet (C group) or a high-fat diet (HF), both with vitamin D, and counterpart groups without vitamin D (VitD- groups), we found in plasma: higher alanine aminotransferase, and aspartate aminotransferase in the VitD- groups, and more elevated total cholesterol in the HF group. Compared to… CONTINUE READING