Vitamin D Deficiency Contributes to the Reduction and Impaired Function of Naïve CD45RA+ Regulatory T Cell in Chronic Heart Failure

@inproceedings{Ma2015VitaminDD,
  title={Vitamin D Deficiency Contributes to the Reduction and Impaired Function of Na{\"i}ve
CD45RA+ Regulatory T Cell in Chronic Heart Failure},
  author={Yan-hui Ma and Yun-lan Zhou and Chao-Yan Yue and Guang-hui Zhang and Lin Deng and Guo-hua Xie and Wei-ping Xu and Li-song Shen},
  booktitle={Journal of immunology research},
  year={2015}
}
The effect of vitamin D pertinent to cardiovascular health on the heart itself is considered to shift toward an anti-inflammatory response in chronic heart failure (CHF); however, its underlying mechanism is not completely understood. In this study, we demonstrated that plasma 25(OH)D level, negatively associated with NT-ProBNP, correlated with the decreased Treg in CHF compared to the patients with other cardiovascular diseases and healthy and older donors. Naïve Treg cell (CD4(+)CD45RA… CONTINUE READING