Vitamin D Deficiency Causes Defective Resistance to Aspergillus fumigatus in Mice via Aggravated and Sustained Inflammation

Abstract

BACKGROUND Vitamin D plays an important role in pulmonary resistance and immunity, and its deficiency has been linked to various respiratory infections. Little is known about the effect of vitamin D deficiency on host pulmonary defense to Aspergillus fumigatus (A. fumigatus). METHODS Mice raised on vitamin D sufficient or deficient diets were infected… (More)
DOI: 10.1371/journal.pone.0099805

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