Vitamin D, vitamin D receptor, and macroautophagy in inflammation and infection.

@article{Wu2011VitaminDV,
  title={Vitamin D, vitamin D receptor, and macroautophagy in inflammation and infection.},
  author={Shaoping Wu and Jun Sun},
  journal={Discovery medicine},
  year={2011},
  volume={11 59},
  pages={325-35}
}
Vitamin D is involved in mineral and bone homeostasis, immune responses, anti-inflammation, anti-infection, and cancer prevention. Vitamin D receptor (VDR) is a nuclear receptor that mediates most biological functions of 1,25(OH)(2)D(3) or vitamin D(3), the active form of vitamin D. Recently, vitamin D(3)-induced autophagy has been reported. Autophagy is a lysosome-mediated catabolic pathway classified into three different types: macroautophagy, microautophagy, and chaperone-mediated autophagy… CONTINUE READING
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