Vitamin C supplementation in very preterm infants: a randomised controlled trial.

@article{Darlow2005VitaminCS,
  title={Vitamin C supplementation in very preterm infants: a randomised controlled trial.},
  author={Brian Alexander Darlow and Hendrikje Buss and Fiona M. McGill and Lynn Fletcher and Patricia Albjerg Graham and Christine C Winterbourn},
  journal={Archives of disease in childhood. Fetal and neonatal edition},
  year={2005},
  volume={90 2},
  pages={F117-22}
}
OBJECTIVE To determine whether regulating vitamin C (ascorbic acid: AA) intake to achieve higher or lower plasma concentrations was associated with improved clinical outcome. DESIGN A double blind, randomised controlled trial. SETTING Neonatal intensive care unit at Christchurch Women's Hospital. PATIENTS Infants with birth weight <1500 g or gestation <32 weeks, admitted to the unit within 48 hours of birth. INTERVENTION Infants were randomised to one of three protocols with regard to… CONTINUE READING
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