Vitamin C Transporters in Cancer: Current Understanding and Gaps in Knowledge

@inproceedings{Wohlrab2017VitaminCT,
  title={Vitamin C Transporters in Cancer: Current Understanding and Gaps in Knowledge},
  author={Christina Wohlrab and Elisabeth Phillips and Gabi Ursula Dachs},
  booktitle={Front. Oncol.},
  year={2017}
}
Sufficient uptake and whole body distribution of vitamin C (ascorbate) is essential for many biochemical processes, including some that are vital for tumor growth and spread. Uptake of ascorbate into cancer cells is modulated by availability, tumor blood flow, tissue diffusion parameters, and ascorbate transport proteins. Uptake into cells is mediated by two families of transport proteins, namely, the solute carrier gene family 23, consisting of sodium-dependent vitamin C transporters (SVCTs) 1… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
1 Citations
78 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 78 references

mechanisms of adaptive regulation in liver epithelial cells

  • JC Reidling, Rubin SA. Promoter analysis of the human ascorbic acid t SVCT1
  • J Nutr Biochem
  • 2011
Highly Influential
7 Excerpts

Similar Papers

Loading similar papers…