Vitamin C: Promises Not Kept

  title={Vitamin C: Promises Not Kept},
  author={Norman B. Duerbeck and David D Dowling and Jillinda M Duerbeck},
  journal={Obstetrical \& Gynecological Survey},
&NA; Vitamin C has been suggested as beneficial in preventing and curing the common cold, decreasing the incidence of preterm delivery and preeclampsia, decreasing risk of cancer and cardiovascular disease, and improving the quality of life by inhibiting blindness and dementia. In this article, we review the hypothesized mechanisms of these purported health benefits and the evidence behind such claims. Target Audience Obstetricians and gynecologists, family physicians. Learning Objectives After… 
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Vitamin C and E supplementation initiated in the 9th to 16th week of pregnancy in an unselected cohort of low-risk, nulliparous women did not reduce the rate of adverse maternal or perinatal outcomes related to pregnancy-associated hypertension.
Vitamin E and C in preeclampsia.
  • S. Kharb
  • Medicine, Biology
    European journal of obstetrics, gynecology, and reproductive biology
  • 2000
Vitamins C and E and the risks of preeclampsia and perinatal complications.
Benefits of supplementation with vitamins C and E during pregnancy do not reduce the risk of preeclampsia in nulliparous women, therisk of intrauterine growth restriction, or the Risk of death or other serious outcomes in their infants.
Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans.
  • A. CarrB. Frei
  • Medicine
    The American journal of clinical nutrition
  • 1999
The totality of the reviewed data suggests that an intake of 90-100 mg vitamin C/d is required for optimum reduction of chronic disease risk in nonsmoking men and women, suggesting a new RDA of 120 mg vitaminC/d.
Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes?
A high vitamin C intake from supplements is associated with an increased risk of cardiovascular disease mortality in postmenopausal women with diabetes.
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