Vitamin C: Promises Not Kept

  title={Vitamin C: Promises Not Kept},
  author={N. Duerbeck and D. Dowling and Jillinda M Duerbeck},
  journal={Obstetrical \& Gynecological Survey},
&NA; Vitamin C has been suggested as beneficial in preventing and curing the common cold, decreasing the incidence of preterm delivery and preeclampsia, decreasing risk of cancer and cardiovascular disease, and improving the quality of life by inhibiting blindness and dementia. In this article, we review the hypothesized mechanisms of these purported health benefits and the evidence behind such claims. Target Audience Obstetricians and gynecologists, family physicians. Learning Objectives After… Expand
The Long History of Vitamin C: From Prevention of the Common Cold to Potential Aid in the Treatment of COVID-19
The most relevant studies from the prevention and treatment of common respiratory diseases to the use of vitamin C in critical illness conditions are summarized, with the aim of clarifying its potential application during an acute SARS-CoV2 infection. Expand
Poor Vitamin C Status Late in Pregnancy Is Associated with Increased Risk of Complications in Type 1 Diabetic Women: A Cross-Sectional Study
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Vitamins C and E to prevent complications of pregnancy-associated hypertension.
Vitamin C and E supplementation initiated in the 9th to 16th week of pregnancy in an unselected cohort of low-risk, nulliparous women did not reduce the rate of adverse maternal or perinatal outcomes related to pregnancy-associated hypertension. Expand
Vitamins C and E and the risks of preeclampsia and perinatal complications
There were no significant differences between the vitamin and placebo groups in the risk of preeclampsia, death or serious outcomes in the infants, and delivering an infant whose birth weight was below the 10th percentile for gestational age. Expand
Vitamin E and C in preeclampsia.
  • S. Kharb
  • Medicine
  • European journal of obstetrics, gynecology, and reproductive biology
  • 2000
In patients with preeclampsia antioxidant nutrients may be utilized to a greater extent to counteract free radical-mediated cell disturbances, resulting in a reduction in serum antioxidant levels. Expand
Vitamins C and E and the risks of preeclampsia and perinatal complications.
Benefits of supplementation with vitamins C and E during pregnancy do not reduce the risk of preeclampsia in nulliparous women, therisk of intrauterine growth restriction, or the Risk of death or other serious outcomes in their infants. Expand
Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans.
  • A. Carr, B. Frei
  • Medicine
  • The American journal of clinical nutrition
  • 1999
The totality of the reviewed data suggests that an intake of 90-100 mg vitamin C/d is required for optimum reduction of chronic disease risk in nonsmoking men and women, suggesting a new RDA of 120 mg vitaminC/d. Expand
Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): randomised placebo-controlled trial
Concomitant supplementation with vitamin C and vitamin E does not prevent pre-eclampsia in women at risk, but does increase the rate of babies born with a low birthweight, and use of these high-dose antioxidants is not justified in pregnancy. Expand
Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes?
A high vitamin C intake from supplements is associated with an increased risk of cardiovascular disease mortality in postmenopausal women with diabetes. Expand
Vitamin C and the Risk of Preeclampsia— Results from Dietary Questionnaire and Plasma Assay
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Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial
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A critical review of vitamin C for the prevention of age-related cognitive decline and Alzheimer's disease.
Overall, there is a large body of evidence that maintaining healthy vitamin C levels can have a protective function against age-related cognitive decline and Alzheimer's disease, but avoiding vitamin C deficiency is likely to be more beneficial than taking supplements on top of a normal, healthy diet. Expand