Vitamin B12, folic acid, and the nervous system

  title={Vitamin B12, folic acid, and the nervous system},
  author={E. Reynolds},
  journal={The Lancet Neurology},
  • E. Reynolds
  • Published 2006
  • Medicine
  • The Lancet Neurology
  • There are many reasons for reviewing the neurology of vitamin-B12 and folic-acid deficiencies together, including the intimate relation between the metabolism of the two vitamins, their morphologically indistinguishable megaloblastic anaemias, and their overlapping neuropsychiatric syndromes and neuropathology, including their related inborn errors of metabolism. Folates and vitamin B12 have fundamental roles in CNS function at all ages, especially the methionine-synthase mediated conversion of… CONTINUE READING