Vitamin B12, folate, and homocysteine in depression: the Rotterdam Study.

  title={Vitamin B12, folate, and homocysteine in depression: the Rotterdam Study.},
  author={Henning Tiemeier and H Ruud van Tuijl and Albert Hofman and Johan Meijer and Amanda J. Kiliaan and Monique M. B. Breteler},
  journal={The American journal of psychiatry},
  volume={159 12},
OBJECTIVE The associations of vitamin B(12), folate, and homocysteine with depression were examined in a population-based study. METHOD The authors screened 3,884 elderly people for depressive symptoms. Subjects with positive screening results had psychiatric workups. Folate, vitamin B(12), and homocysteine blood levels were compared in 278 persons with depressive symptoms, including 112 with depressive disorders, and 416 randomly selected reference subjects. Adjustments were made for age… 

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