Corpus ID: 32247334

Vitamin B 12 Levels of Cerebrospinal Fluid in Patients with Organic Mental Disorder

@inproceedings{Tiggelen2007VitaminB1,
  title={Vitamin B 12 Levels of Cerebrospinal Fluid in Patients with Organic Mental Disorder},
  author={C. Tiggelen and J. Peperkamp and J. Tertoolen},
  year={2007}
}
Introduction A wide range of psychiatric symptoms has been associated with pernicious anemia. A number of factors indicate a causal relationship between B12 deficiency and cerebral dysfunction and consequent organic mental change. Deana (1977) demonstrated that vitamin B12 deficiency in the rat has profound effects on several neurotransmitter systems and results in significantly reduced norepinephrine levels in the brain. Uncorrected vitamin B12 deficiency may result in dementia and cerebral… Expand
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