Vitamin A status in preschool-age Indonesian children as assessed by the modified relative-dose-response assay.

@article{Tanumihardjo1990VitaminAS,
  title={Vitamin A status in preschool-age Indonesian children as assessed by the modified relative-dose-response assay.},
  author={Sherry Ann Tanumihardjo and Muhilal and Y. Yuniar and Dewi Permaesih and Zein Sulaiman and D. Basta S. Karyadi and James A. Olson},
  journal={The American journal of clinical nutrition},
  year={1990},
  volume={52 6},
  pages={
          1068-72
        }
}
The modified relative-dose-response (MRDR) assay has been validated in rats as a function of vitamin A status and tested in a group of American children. In this study the MRDR assay was applied to West Javan children who are at risk of being vitamin A deficient. Of 86 children enrolled, 75 were tested. In a time-course study involving 22 children aged 3.7-5.3 y, blood samples were taken at different times after doses of 0.35 mumol 3,4-didehydroretinyl acetate/kg body wt. Generally, the ratio… CONTINUE READING
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