Vitamin A deficiency is associated with hepatitis C virus chronic infection and with unresponsiveness to interferon-based antiviral therapy.

@article{Bitetto2013VitaminAD,
  title={Vitamin A deficiency is associated with hepatitis C virus chronic infection and with unresponsiveness to interferon-based antiviral therapy.},
  author={Davide Bitetto and Nadia Bortolotti and Edmondo Falleti and Sara Vescovo and C. Fabris and Giovanna Fattovich and Annarosa Cussigh and Sara Cmet and Ezio Fornasiere and Elisa Ceriani and Mario Pirisi and Pierluigi Toniutto},
  journal={Hepatology},
  year={2013},
  volume={57 3},
  pages={925-33}
}
UNLABELLED Recent data suggest that vitamin A modulates the expression of type I interferon receptor enhancing the antireplication effect of interferon-α on hepatitis C virus (HCV). This study aimed to investigate the prevalence of vitamin A deficiency among patients with chronic HCV infection and to assess whether vitamin A deficiency could be associated with unresponsiveness to interferon-based antiviral therapy. The analysis included 199 consecutive treatment-naïve chronic HCV patients in… CONTINUE READING
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