Vitamin A at pharmacologic doses ameliorates the membrane lipid peroxidation injury and testicular atrophy that occurs with chronic alcohol feeding in rats.

Abstract

The interaction of ethanol (ETOH) with testicular subcellular membranes contributes, at least in part, to alcohol-induced gonadal dysfunction. Vitamin A reaches the testes via the circulation as the retinyl ester and is converted to the free alcohol (retinol) and then to the aldehyde (retinal); retinal is the form of the vitamin which is essential for… (More)

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