Vitamin A and iron supplementation is as efficient as hormonal therapy in constitutionally delayed children

@article{Zadik2004VitaminAA,
  title={Vitamin A and iron supplementation is as efficient as hormonal therapy in constitutionally delayed children},
  author={Zvi Zadik and Tali Sinai and Amnon Zung and Ram M. Reifen},
  journal={Clinical Endocrinology},
  year={2004},
  volume={60}
}
objective  To assess the effect of nutritional supplementation on growth and puberty in constitutionally delayed children. 

Vitamins and Trace Elements are Important for the Integrity of the Endocrine System

  • Z. Zadik
  • Medicine, Biology
    Journal of pediatric endocrinology & metabolism : JPEM
  • 2009
A study conducted in northern Finland looking into the incidence of type 1 diabetes mellitus among a pediatric cohort showed a statistical difference between those with inadequate vitamin D during infancy and childhood and those who received vitamin D supplementation, favoring adequate vitamin D intake as a preventive measure to preventabetes mellitus.

Evidence for hypermetabolism in boys with constitutional delay of growth and maturation.

Boys with CDGM have higher rates of overall energy expenditure compared with age- and size-matched controls, and this increased metabolism may result in impaired tempo of growth.

The Impact of Nutritional Interventions beyond the First 2 Years of Life on Linear Growth: A Systematic Review and Meta-Analysis.

It is suggested that zinc, vitamin A, multiple micronutrients, and protein interventions delivered after 24 mo of age can have a positive effect on linear growth, especially in populations that have experienced growth failure.

Nutritional interventions during adolescence and their possible effects.

This mini review sums up some important findings in this important complex that link between nutrition, nutritional interventions, and pubertal development.

A Double-Blind, Placebo-Controlled Comparison of Letrozole to Oxandrolone Effects upon Growth and Puberty of Children with Constitutional Delay of Puberty and Idiopathic Short Stature

This first randomized controlled clinical trial in CDGD teenage boys with predicted short stature shows that letrozole increases PAH more than oxandrolone and advances pubertal stage and bone mineralization less.

Constitutional Delay of Growth and Puberty: the Patient's Perspective

Evaluating the concerns, knowledge, understanding, and expectations of a group of children with CDGP and their families finds that short stature rather than late puberty is usually the reason for consultation in CDGP.

“Functional Food” for Acceleration of Growth in Short Children Born Small for Gestational Age

Six months of vitamin A, iron and zinc supplementation induces growth acceleration in short children born SGA with subnormal nutrients intake similar to growth hormone therapy.

Reduced Final Height and Inadequate Nutritional Intake in Cow's Milk-Allergic Young Adults.

Nutritional Determinants of the Timing of Puberty.

Evidence for prenatal nutrition, infant feeding practices, and childhood intake of fat, carbohydrate, and micronutrients is inconsistent and secondary analyses of prenatal and early-life randomized nutritional interventions with extended follow-up through peripubertal years would help clarify the role of nutrition.

A Clinical Study on the Treatment of Children's Short Stature with Auxiliary Comprehensive Management Combined with Growth Patch

On the basis of auxiliary comprehensive management combined with growth patch for the treatment of children with ISS, it can effectively increase the height of the children, improve the levels of serum IGF-1 and IGFBP-3, and have significant clinical effects, which is beneficial to the healthy growth of theChildren.

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