Vitamin A ameliorates the genotoxicity in mice of aflatoxin B1-containing Aspergillus flavus infested food.

Abstract

Young weaning Swiss albino mice were orally administered crude aflatoxin B1 in a dose mimicking human exposure condition, i.e. at 0.05 micrograms/kg body weight/day for 14 weeks. Vitamin A (retinol) was orally administered along with the toxin in double (132 IU/kg body wt/day) the human equivalent therapeutic dose. The results suggested that vitamin A… (More)

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