Vitamin A Metabolism: An Update

  title={Vitamin A Metabolism: An Update},
  author={Diana N. D’Ambrosio and R. Clugston and W. Blaner},
  pages={63 - 103}
  • Diana N. D’Ambrosio, R. Clugston, W. Blaner
  • Published 2011
  • Medicine, Biology
  • Nutrients
  • Retinoids are required for maintaining many essential physiological processes in the body, including normal growth and development, normal vision, a healthy immune system, normal reproduction, and healthy skin and barrier functions. In excess of 500 genes are thought to be regulated by retinoic acid. 11-cis-retinal serves as the visual chromophore in vision. The body must acquire retinoid from the diet in order to maintain these essential physiological processes. Retinoid metabolism is complex… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    STRA6 is critical for cellular vitamin A uptake and homeostasis.
    • 62
    • Open Access
    Vitamin A Deficiency and the Lung
    • 23
    • Open Access


    Publications referenced by this paper.
    Retinyl Ester Formation by Lecithin:Retinol Acyltransferase Is a Key Regulator of Retinoid Homeostasis in Mouse Embryogenesis*
    • 72
    • Open Access
    Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin*
    • 68
    • Open Access
    Impaired retinal function and vitamin A availability in mice lacking retinol‐binding protein
    • 431
    • Open Access
    In vitro and in vivo characterization of retinoid synthesis from beta-carotene.
    • 46
    • Open Access
    Acidic retinoids synergize with vitamin A to enhance retinol uptake and STRA6, LRAT, and CYP26B1 expression in neonatal lung
    • 53
    • Open Access
    Pathways of vitamin A delivery to the embryo: insights from a new tunable model of embryonic vitamin A deficiency.
    • 120
    • Open Access
    Cellular retinol‐binding protein I is essential for vitamin A homeostasis
    • 293
    • Highly Influential
    • Open Access
    Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice.
    • 21
    • Open Access