Vitamin C

  title={Vitamin C},
  author={Carole L. Linster and E. Van Schaftingen},
  journal={The FEBS Journal},
  • Carole L. Linster, E. Van Schaftingen
  • Published 2007
  • Chemistry, Medicine
  • The FEBS Journal
  • Vitamin C, a reducing agent and antioxidant, is a cofactor in reactions catalyzed by Cu+‐dependent monooxygenases and Fe2+‐dependent dioxygenases. It is synthesized, in vertebrates having this capacity, from d‐glucuronate. The latter is formed through direct hydrolysis of uridine diphosphate (UDP)‐glucuronate by enzyme(s) bound to the endoplasmic reticulum membrane, sharing many properties with, and most likely identical to, UDP‐glucuronosyltransferases. Non‐glucuronidable xenobiotics… CONTINUE READING
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