Vitamin A responsive night blindness in Dent’s disease

@article{Sethi2009VitaminAR,
  title={Vitamin A responsive night blindness in Dent’s disease},
  author={Sidharth Kumar Sethi and M. Ludwig and Madhulika Kabra and Pankaj Hari and Arvind Bagga},
  journal={Pediatric Nephrology},
  year={2009},
  volume={24},
  pages={1765-1770}
}
Dent’s disease is an X-linked renal tubular disorder characterized by low molecular weight proteinuria, hypercalciuria and nephrocalcinosis or nephrolithiasis. The disease is caused by mutations in a renal chloride channel gene, CLCN5. We report on three boys, of Indian origin, with Dent’s disease that presented at an early age (1–4 years), with polyuria, polydipsia, salt craving, recurrent vitamin A-responsive night blindness, hypophosphataemic rickets, hypercalciuria and low molecular weight… CONTINUE READING